Cysteine hydrochloride

2024-05-10by admin0

Cysteine ​​hydrochloride structural formula

Structural formula

Business number 015R
Molecular formula C3H8ClNO2S
Molecular weight 157.62

L-cysteine ​​hydrochloride,

L-cysteine ​​hydrochloride hydrate,

Alpha-amino-beta-mercaptopropionic acid hydrochloride,

L-cysteine ​​hydrochloride,

fu amino acid,

L-mercaptoalanine hydrochloride anhydrous,

L-Cysteine ​​hydrochloride,

Cysteine ​​HCl,

2-Amino-3-mercaptopropanoic acid,


Biochemical reagents

Numbering system

CAS number:52-89-1

MDL number:MFCD00064553

EINECS number:200-157-7

RTECS number:HA2275000

BRN number:3560277

PubChem number:24892395

Physical property data

1. Character: White crystal. Hygroscopic.

2. Density (g/mL, 25/4℃): Not determined

3. Relative vapor density (g/mL, air=1): Not determined Determined

4. Melting point (ºC): 175~178℃ (decomposition)

5. Boiling point (ºC, normal pressure): Undetermined

6. Boiling point (ºC, 13.33kpa):

7. Refractive index: Not determined

8. Flash point (ºC): Not determined

9. Specific rotation Degree (º,): 5.0° (5mol/L, in hydrochloric acid)

10. Autoignition point or ignition temperature (ºC): Undetermined

11. Vapor pressure (kPa , 25ºC): Undetermined

12. Saturated vapor pressure (kPa, 60ºC): Undetermined

13. Heat of combustion (KJ/mol): Undetermined

14. Critical temperature (ºC): Undetermined

15. Critical pressure (KPa): Undetermined

16. Log value of oil-water (octanol/water) partition coefficient : Undetermined

17. Explosion upper limit (%, V/V): Undetermined

18. Explosion lower limit (%, V/V): Undetermined

19. Solubility: Soluble in water, ethanol and acetone. Aqueous solutions are acidic.

Toxicological data

1. Acute toxicity: mouse abdominal LC50: 1250 mg/kg; mouse intravenous LC50: 771 mg/kg; mouse LC50: 3 mg/kg; 2. Mutagenicity: mutation microorganismsTEST system: bacteria – Salmonella typhimurium: 20mg/plate; Cytogenetic analysisTEST system: rodents�-Hamster fibroblasts: 2mg/L

Ecological data

None yet

Molecular structure data

1. Molar refractive index: 28.90

2. Molar volume (cm3/mol): 90.7

3. Isotonic specific volume (90.2K ): 251.5

4. Surface tension (dyne/cm): 58.9

5. Polarizability (10-24cm3): 11.45

Compute chemical data

1. Reference value for hydrophobic parameter calculation (XlogP): None

2. Number of hydrogen bond donors: 4

3. Number of hydrogen bond acceptors: 4

4. Number of rotatable chemical bonds: 2

5. Number of tautomers: none

6. Topological molecule polar surface area 64.3

7. Number of heavy atoms: 8

8. Surface charge: 0

9. Complexity: 75.3

10. Number of isotope atoms: 0

11. Determine the number of atomic stereocenters: 1

12. Uncertain number of atomic stereocenters: 0

13. Determine the number of chemical bond stereocenters: 0

14. Number of uncertain chemical bond stereocenters: 0

15. Number of covalent bond units: 2

Properties and stability

Hygroscopic. Oxidizes and decomposes slowly in air. Aqueous solutions are acidic.

Storage method

Should be sealed and stored in a cool, dry place away from light.

Synthesis method

1. Dissolve cystine in dilute hydrochloric acid, filter and add tin particles to heat and reflux. Dilute the reducing solution with water, remove the remaining tin particles, saturate with hydrogen sulfide, filter, wash the filter residue with a small amount of water, combine the washing liquid and filtrate, concentrate under reduced pressure, cool and crystallize, and dry to obtain L-cysteine ​​hydrochloride.

2. Hydrolyzed by α-keratin contained in hair Cystine can be obtained, and then reduced to cysteine ​​through chemical reduction or electrolysis, and hydrochloric acid is added to form a salt.


1. Used for biochemical research. Determination of calcium and magnesium in steel raw materials. Reducing agent for determination of hemolysin. Growth culture and enumeration of anaerobic bacteria.

2.Used in biochemistry Research. Determination of calcium and magnesium in steel raw materials. Reducing agent for determination of hemolysin. It is used to treat acrylonitrile and aromatic poisoning, prevent radiation damage, treat bronchitis and reduce phlegm. It is also used in cosmetics to prevent aging, and as a food additive to promote fermentation and maintain umami taste.

3.Used as analytical reagents, As a masking agent, it is used to measure calcium and magnesium. It can be used as a reducing agent for biochemical research, such as hemolysin determination. Also used for the cultivation of anaerobic bacteria.


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